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I have been on Meridia 10 mg for approximately a week and a half. The only side effect that I have had is jittery sleep (i.e. I wake up a few times throughout the night and am very alert but can go right back to sleep - its odd! I am usually a VERY heavy sleeper) but this is no deal-breaker...Meridia has already been extremely effective - I have lost 6 pounds in a week and a half. I am about 40 lbs overweight so I still have a long way to go but it is such a relief that this is getting the ball rolling - the weight loss finally feels surmountable. Other reviewers are certainly correct - you do have to put in effort on this medication - it isn't a magic pill. I have stuck religiously to a 1200 cal diet & cardio for 30 min 5 days/week.

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I have been on Meridia for one year under my doctor's supervision. During that time I have lost 108 pounds. My doctor has been able to gradually take me off of all 3 blood pressure prescriptions, simvastatin and metformin. It has been very effective in helping me control my appetite and thus lose weight. I have increased energy, sex drive, and generally a much better disposition and outlook on life. It has been great for me. I have another 12 pounds to lose to reach my goal weight of 174. Once that is achieved, he intends to keep me on Meridia for another 6 months to enable my body to achieve the correct amount of Leptin production necessary to maintain my new weight and prevent me from regaining the 120 lbs I will have lost.

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There are several mechanisms in which obesity might cause hypertension.

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