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What caused Michael J Fox's Parkinson's disease? Michael J. Fox, who was diagnosed when he was 30 years old, is in this category. People with Parkinson's disease have a shortage of a chemical that affects movement (called dopamine) in their brains. This is caused by changes in the cells of the substantia nigra, the area of the brain that produces dopamine.
How do anticholinergic drugs for Parkinson's disease work? Anticholinergics may be given alone, or with levodopa or dopamine agonists in people with more advanced disease who have a persistent tremor. There are several anticholinergic drugs available for people with Parkinson disease, including trihexyphenidyl, benztropine, orphenadrine, procyclidine, and biperiden.
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