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Are there any other enzyme deficiencies that would cause congenital adrenal hyperplasia? Congenital adrenal hyperplasia (CAH) is a group of rare inherited autosomal recessive disorders characterized by a deficiency of one of the enzymes needed to make specific hormones. The most common cause of CAH is the absence of the enzyme 21-hydroxylase.
Can CAH be cured? Right now, there is no cure for CAH, but there is treatment. Some people with mild CAH may not need to take medicine all the time.
Can Cushings lead to Addison's? Addison's disease is marked by deficiencies of aldosterone and cortisol, hormones produced in the adrenal glands. Aldosterone deficiency impairs water and sodium retention, which may lead to dehydration and hypovolemic shock. Addison's disease most often stems from an autoimmune response related to infection or cancer.
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