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What does a tumor feel like in your stomach? An abdominal mass causes visible swelling and may change the shape of the abdomen. A person with an abdominal mass may notice weight gain and symptoms such as abdominal discomfort, pain, and bloating. Masses in the abdomen are often described by their location.
Are GIST tumors common? Current estimates for the total number of GIST cases each year in the United States range from about 4,000 to about 6,000. These tumors can start anywhere in the GI tract, but they occur most often in the stomach (about 60%) or the small intestine (about 35%). GISTs are most commonly found in people in their 60s.
What causes GIST Cancer? A few families have gastrointestinal stromal tumors (GISTs) caused by a gene mutation passed down from parent to child. (See Gastrointestinal Stromal Tumor Risk Factors.) But most gene mutations related to GISTs are not inherited. These changes occur for no apparent reason, and are called acquired or sporadic.
Can GIST tumors be cured? In nearly all patients, there is no apparent reason why GIST has developed. In fact, patients with metastatic GIST treated with imatinib mesylate now have a 2 year survival of about 80% from the time of metastasis. The prognosis of a patient with primary GIST depends on tumor size, location, and cellular division.
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