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What is the function of tacrolimus? Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.
What is the mechanism of action of tacrolimus? Tacrolimus bonds to an immunophilin, FK506 binding protein (FKBP). This complex inhibits calcineurin phosphatase. The drug inhibits calcium-dependent events, such as interleukin-2 gene transcription, nitric oxide synthase activation, cell degranulation, and apoptosis.
What does tacrolimus treat? Tacrolimus is an immunosuppressant. It works by decreasing your body's immune system. Tacrolimus topical (for the skin) is used to treat severe atopic dermatitis (eczema). Tacrolimus may also be used for purposes not listed in this medication guide.
How much is a generic z pack? Generic azithromycin is covered by most Medicare And insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest GoodRx price for the most common version of generic Zithromax is around $4.80, 87% off the average retail price of $37.22.
What are the risks of taking immunosuppressants? The most significant side effect of immunosuppressant drugs is an increased risk of infection. Other, less serious side effects can include loss of appetite, nausea, vomiting, increased hair growth, and hand trembling. These effects typically subside as the body adjusts to the immunosuppressant drugs.
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